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Description
Metformin
Metformin stands as a cornerstone in the management of type 2 diabetes mellitus, offering effective glycemic control while mitigating the risk of hypoglycemia. With its additional benefits in weight management and off-label use in PCOS, Metformin emerges as a versatile and indispensable therapeutic option in the realm of diabetes care.
Primary Uses
- Type 2 Diabetes Management: Metformin serves as a cornerstone in the pharmacotherapy of type 2 diabetes mellitus, aiding in the regulation of blood glucose levels.
- Off-Label Use: Additionally, it finds off-label application in addressing insulin resistance associated with polycystic ovary syndrome (PCOS), broadening its therapeutic scope.
Mechanism of Action
- Antihyperglycemic Properties: Metformin effectively reduces blood glucose levels in type 2 diabetes without inducing hypoglycemia, making it a preferred choice in pharmacotherapy.
- Insulin Sensitization: Acting as an “insulin sensitizer,” Metformin mitigates insulin resistance, leading to a notable decrease in fasting insulin levels and improved glycemic control.
Therapeutic Benefits
- Weight Management: Metformin offers the additional benefit of modest weight loss, particularly advantageous for obese patients with type 2 diabetes.
- Comprehensive Approach: Its multifaceted action, encompassing glycemic control and weight management, renders Metformin an invaluable asset in diabetes management.